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Alligators, which often engage in violent fights over territories and mates, have made scientists puzzled why their wounds rarely get infected. Now researchers think the secret lies in the reptiles’ blood. Chemists in Louisiana found that blood from the American alligator can successfully destroy 23 strains of bacteria, including strains known to be resistant to antibiotics. In addition, the blood was able to deplete and destroy a significant amount of HIV, the virus that causes AIDS.
Study co-author Lancis Darville at Louisiana State University in Baton Rouge believes that peptides – fragments of proteins – within alligator blood help the animals stop fatal infections. Such peptides are also found in the skin of frogs and toads, as well as komodo, dragons and crocodiles. The scientists think that these peptides could one day lead to medicines that would provide humans with the same antibiotic protection. ’We are in the process of separating and identifying the specific peptides in alligator blood,’ said Darville. ’Once we sequence these peptides, we can obtain their chemical structure to potentially create new drugs.’
Study co-author Mark Merchant, a biochemist at McNeese State University in Lake Charles, Louisiana, was among the first to notice alligators’ unusual resistance. He was intrigued that, despite living in swampy environments where bacteria thrive, alligators that suffered frequent scratches and bruises rarely developed fatal infections. Merchant therefore created human and alligator serum-protein-rich blood plasma that has been able to remove clotting agents, and exposed each of them to 23 strains of bacteria. Human serum destroyed only eight of the bacterial strains while the alligator serum killed all 23. When the alligator was exposed to HIV, the researchers found that a good amount of the virus was destroyed.
The study team thinks that pills and creams containing alligator peptides could be available at level pharmacies within seven to ten years. Such products would be a solution to patients that need extra help preventing infections, such as diabetes patients with foot ulcers, burn victims and people suffering from autoimmune diseases. However, there may be potential problems before alligator-based medicines can reach drugstore shelves. For example, initial tests have revealed that higher concentrations of the alligator serum tend to be toxic to human cells.
Which of the following statements is NOT TRUE about peptides within alligators’ blood? (SIMAK – 2013)
They are fragments of proteins.
They may stop fatal infections.
They are injected in the human body.
They are within the blood of reptiles.
They have the same function as antibiotics.
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