In the ongoing aunt for more effective weapon against malaria, international researchers said Thursday they are exploring a pathway that has until now been little studied- killing parasites in the liver before the illness emerges. "Its very difficult to work on the liver stages", said Elizabeth Winzeler, professor of pharmacology and drug discovery at University of California Can Diego School of Medicine. "We have traditionally looked for medicine that will cure malaria" she told AFP For the latest research, published in the journal Science, scientists dissected hundreds of thousands of mosquitoes to remove parasites inside them. Each parasite was then isolated in a tube and treated with a different chemicals compound-500,000 experiments in all. Researchers found that certain molecules were able to kill the parasites. After around six years of work, 631 candidates molecules for a chemicals vaccine have been identified-a normal vaccine that would allow the body to make antibodies. "If you could find a drug that you give on one day at one time that will kill all the malaria parasites in the person, both in the liver and in the bloodstream, and last for three to six months. Year, that be super but there is no drug like that right now," said Larry Slutsker e reader of PATHs Malaria and Neglected Tropical Diseases (ntds) programmes. Reducing the number of does is crucial. That's because many medication available today must be taken over three days, said David Ready, leo of Medicine for Malaria Ventured. But often, after the first dose, a child begins to feel better and the never lessons. Parents then keep the other two does in case another of their chidren falls ill. "That has two impacts. First the child does not get cured properly and secondly it builds drug resistance," Reddy said. What will happen to child who suffer from malaria if his/her parent reduces the number of medicine doses?

Question

In the ongoing aunt for more effective weapon against malaria, international researchers said Thursday they are exploring a pathway that has until now been little studied- killing parasites in the liver before the illness emerges.

"Its very difficult to work on the liver stages", said Elizabeth Winzeler, professor of pharmacology and drug discovery at University of California Can Diego School of Medicine.

"We have traditionally looked for medicine that will cure malaria" she told AFP

For the latest research, published in the journal Science, scientists dissected hundreds of thousands of mosquitoes to remove parasites inside them. Each parasite was then isolated in a tube and treated with a different chemicals compound-500,000 experiments in all.

Researchers found that certain molecules were able to kill the parasites. After around six years of work, 631 candidates molecules for a chemicals vaccine have been identified-a normal vaccine that would allow the body to make antibodies.

"If you could find a drug that you give on one day at one time that will kill all the malaria parasites in the person, both in the liver and in the bloodstream, and last for three to six months. Year, that be super but there is no drug like that right now," said Larry Slutsker e reader of PATHs Malaria and Neglected Tropical Diseases (ntds) programmes.

Reducing the number of does is crucial. That's because many medication available today must be taken over three days, said David Ready, leo of Medicine for Malaria Ventured. But often, after the first dose, a child begins to feel better and the never lessons. Parents then keep the other two does in case another of their chidren falls ill.

"That has two impacts. First the child does not get cured properly and secondly it builds drug resistance," Reddy said.

What will happen to child who suffer from malaria if his/her parent reduces the number of medicine doses?