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At an early age, Marie displayed a brilliant mind and a blithe personality. Her great exuberance for learning prompted her to continue with her studies after high school. ____, she became disgruntled when she learned that the university in Warsaw was closed to women. Determined to receive a higher education, she defiantly left Poland and in 1891 entered the Sorbonne, a French university where she earned her master’s degree and doctorate in physics.
The most appropriate word to complete the paragraph is ….
despite
however
although
moreover
in spite of
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