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A mouse that cured A new ally against cancer Dr. Megan Sykes, a medical researcher, has a mouse with a human immune system – her own. She calls it “Mini- Me.” There are also mice containing a part of9-year-old Michael Feeney- a cancerous tumorextracted from his lungs. Researches have tasted various drugs on the mice, hoping to find the treatment that would work best for Michael. In what could be the ultimate in personalized medicine, animals bearing your disease, or part of your anatomy, can serve as your personal guinea pig, so to speak. Some researches call them avatars, like the virtual characters in movies and online games. “The mice allow you the opportunity to test drugs to find out which ones will be efficacious without exposing the patient to toxicity,” said Colin Collins, a professor at the University of British Columbia. Experiments on mice have been done for decades, including implanting people’s tumors into the animals. But the techniques have improved in the past few years and interest is growing. The National Institutes of Health in Bethesda, Maryland, held a workshop on personalized animal models which are mainly being used for research. Companies are beginning to commercialize them for use in drug development and medical treatment as well. Experts caution that it has not been proved that the use of avatars will prolong the lives of cancer patients. And it costs tens of thousands of dollars, which insurer will not cover, to create and test a colony of the animals. ‘It’s an act of faith to say this is a superior way of proceeding,” said Dr. Edward Sausville, a professor of medicine at the University of Maryland. What is the text about?

A mouse that cured

A new ally against cancer

            Dr. Megan Sykes, a medical researcher, has a mouse with a human immune system – her own. She calls it “Mini- Me.”

            There are also mice containing a part of 9-year-old Michael Feeney- a cancerous tumor extracted from his lungs. Researches have tasted various drugs on the mice, hoping to find the treatment that would work best for Michael.

            In what could be the ultimate in personalized medicine, animals bearing your disease, or part of your anatomy, can serve as your personal guinea pig, so to speak. Some researches call them avatars, like the virtual characters in movies and online games.

            “The mice allow you the opportunity to test drugs to find out which ones will be efficacious without exposing the patient to toxicity,” said Colin Collins, a professor at the University of British Columbia.

            Experiments on mice have been done for decades, including implanting people’s tumors into the animals. But the techniques have improved in the past few years and interest is growing. The National Institutes of Health in Bethesda, Maryland,  held a workshop on personalized animal models which are mainly being used for research. Companies are beginning to commercialize them for use in drug development and medical treatment as well.

            Experts caution that it has not been proved that the use of avatars will prolong the lives of cancer patients. And it costs tens of thousands of dollars, which insurer will not cover, to create and test a colony of the animals.

            ‘It’s an act of faith to say this is a superior way of proceeding,” said Dr. Edward Sausville, a professor of medicine at the University of Maryland.

 

What is the text about?

  1. The commercialization of the mice for drugs development.


  2. The use of mice in medical research against cancer.


  3. The implanting people’s disease into animal.


  4. Human immune system called mini me.

  5. The drugs treatment on the mice.

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A. Setyawan

Master Teacher

Mahasiswa/Alumni Universitas Sebelas Maret

Jawaban terverifikasi

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Pembahasan

Wacana tersebut membahas tentang seekor tikus bernama Mini-Me yang memiliki kekebalan tubuh manusia yang merupakan bagian dari penelitian yang dilakukan oleh Dr. Megan Sykes untuk digunakan dalam eksperimen menguji obat-obatan yang akan digunakan untuk mengobati kanker dan berbagai macam penyakit manusia lainnya. Berdasarkan intisari tersebut, dapat diketahui bahwa tikus digunakan dalam riset pengembangan obat dan perawatan medis sehingga pilihan jawaban (A) adalah yang paling tepat. Pilihan jawaban (B) salah karena tikus tidak hanya digunakan dalam riset melawan kanker, tetapi lebih pada fungsi tubuhnya untuk menguji keampuhan obat dan reaksinya, (C) salah karena teks tidak berfokus pada upaya penanaman penyakit manusia pada hewan meskipun hal tersebut disebutkan, tetapi hanya sebagai informasi penjelas, (D) salah karena Mini-Me adalah nama tikus milik Dr. Megan Sykes dan (E) salah karena kalimat pemakaian obat pada tikus terlalu umum dan tidak menyebutkan secara spesifik terkait kegunaan obat itu pada tikus.

Wacana tersebut membahas tentang seekor tikus bernama Mini-Me yang memiliki kekebalan tubuh manusia yang merupakan bagian dari penelitian yang dilakukan oleh Dr. Megan Sykes untuk digunakan dalam eksperimen menguji obat-obatan yang akan digunakan untuk mengobati kanker dan berbagai macam penyakit manusia lainnya. Berdasarkan intisari tersebut, dapat diketahui bahwa tikus digunakan dalam riset pengembangan obat dan perawatan medis sehingga pilihan jawaban (A) adalah yang paling tepat. Pilihan jawaban (B) salah karena tikus tidak hanya digunakan dalam riset melawan kanker, tetapi lebih pada fungsi tubuhnya untuk menguji keampuhan obat dan reaksinya, (C) salah karena teks tidak berfokus pada upaya penanaman penyakit manusia pada hewan meskipun hal tersebut disebutkan, tetapi hanya sebagai informasi penjelas, (D) salah karena Mini-Me adalah nama tikus milik Dr. Megan Sykes dan (E) salah karena kalimat pemakaian obat pada tikus terlalu umum dan tidak menyebutkan secara spesifik terkait kegunaan obat itu pada tikus.

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