Also known as Hutchinson-Gilford Syndrome, Progeria Syndrome's an extremely rare genetic disease. In this disease the aging process of the body accelerates much faster than what it does in normal humans. This process of aging *gallops* to about seven times the normal rate. Because of this, a child of ten years would have a look of 70 years old. He or she may also have similar respiratory, cardiovascular, and arthritic conditions that a 70-year-old would have. There is no cure for this disease. The exact cause is unknown, but it is believed due to a single abnormal (mutant) gene. Normally for each gene there are two copies, one from each parent. Progeria is considered to be the result of a dominant mutation because the gene in question has one normal copy and one abnormal copy, as opposed to a recessive mutation in which both copies are abnormal. Because neither parent carries or expresses the mutation, each case is believed to represent a sporadic new mutation which happens at the time of conception. Progeria affects between 1 in 8 million (approx) children, with a total reported incidence of just over 1 00 in the century since it has been identified. There are currently between 30 and 40 known cases worldwide of Progeria. Children from all races and cultures from around the world have been affected. Because of the lack of a specific laboratory test at this time, the diagnosis must be based on the physical appearance of the individual. The diagnosis is usually made in the first or second year of life when skin changes and failure to gain weight become *apparent*. Research indicates that a chemical (hyaluronic acid) may befound in greatly elevated levels in the urine of Hutchinson Gilford Progeria Syndrome patients. The same abnormality has been found in Werner Syndrome, which is sometimes called 'progeria of the adult'. (Adapted from various sources - PTT BPPK) The author's main purpose in the passage is to .... A. show the cause of Progeria syndrome B. state the result of Progeria syndrome research C. give examples about the spread of Progeria syndrome D. give explanation about Progeria syndrome E. to scare the reader how dangerously of Progeria syndrome

Halo, Siti. Kakak bantu jawab, ya. Jawaban yang tepat untuk soal ini adalah D. give explanation about Progreria syndrome. Soal ini menanyakan tujuan utama penulis menuliskan teks yang tertera. Teks di soal ini intinya membahas informasi seputar sindrom Progreria. Paragraf 1 membahas gambaran secara umum mengenai seperti apa sindrom Progreria itu. Sebagai contoh, salah satu kalimatnya tertulis sebagai berikut: "Also known as Hutchinson-Gilford Syndrome, Progeria Syndrome's an extremely rare genetic disease" artinya "Dikenal juga sebagai Sindrom Hutchinson-Gilforn, Sindrom Progreria adalah penyakit genetik yang sangat langka". Paragraf 2 membahas asal mula penyebab adanya sindrom Progreria pada manusia. Sebagai contoh, salah satu kalimatnya tertulis sebagai berikut: "The exact cause is unknown, but it is believed due to a single abnormal (mutant) gene" artinya "Penyebab pastinya tidak diketahui, tapi dipercaya merupakan hasil dari gen tunggal yang abnormal (mutan)". Paragraf 3 membahas kasus penderita sindrom Progreria di dunia. Sebagai contoh, salah satu kalimatnya tertulis sebagai berikut: "There are currently between 30 and 40 known cases worldwide of Progeria" artinya "Sekarang ini ada sekitar 30 sampai 40 kasus Progreria yang diketahui di seluruh dunia". Paragraf 4 membahas cara mendiagnosa sindrom Progreria. Sebagai contoh, salah satu kalimatnya tertulis sebagai berikut: "Because of the lack of a specific laboratory test at this time, the diagnosis must be based on the physical appearance of the individual" artinya "Karena kurangnya pengujian laboratorium yang spesifik pada saat ini, diagnosa harus berdasarkan tampilan fisik penderita". Paragraf 5 membahas hasil penelitian terkait kemiripan sindrom Progreria dengan sindrom Werner. Sebagai contoh, salah satu kalimatnya tertulis sebagai berikut: "The same abnormality has been found in Werner Syndrome, which is sometimes called 'progeria of the adult'" artinya "Keabnormalan yang sama telah ditemukan pada sindrom Werner yang terkadang disebut 'progreria dewasa'". Berdasarkan penjelasan tersebut, dapat disimpulkan bahwa teks di soal ini intinya berfungsi untuk memberikan penjelasan mengenai sindrom Progreria. Hal ini sesuai dengan pilihan D. Jadi, jawaban yang benar adalah D. give explanation about Progreria syndrome.